Bonomarlot is a peptide bioregulator derived from the bone marrow of young animals. It is designed to help restore and maintain healthy blood cell production, which is critical for immunity, oxygen transport, and healing. Bonomarlot may support overall vitality and resilience, especially during recovery or aging. Bonomarlot is part of the Cytomax family of tissue-specific peptide bioregulators. It contains short-chain peptides isolated from bone marrow tissue, which play a key role in stimulating hematopoiesis, which is the process by which the body produces red blood cells, white blood cells, and platelets. As the hematopoietic system can become impaired due to aging, illness, or medical treatments like chemotherapy, Bonomarlot helps restore natural regulatory signals needed for optimal function. By supporting healthy blood cell formation, Bonomarlot not only improves immune response and oxygen delivery, but also contributes to tissue regeneration and systemic resilience. It is often considered in protocols for immune support, recovery from fatigue or chronic illness, and healthy aging.
Bonomarlot
Also known as: A-20 Bone Marrow Peptide Bioregulator
Overview
Benefits
- Increases production of red and white blood cells
- Supports immune defense and response to infection
- Enhances energy, stamina, and systemic recovery
- Aids in post-illness and post-chemotherapy regeneration
- Promotes longevity by restoring hematopoietic efficiency
Consider This Peptide If You Want To
- Recovering from anemia, chemotherapy, or other causes of low blood cell counts
- Want to strengthen your immune system
- Support your body's ability to regenerate and stay resilient with age
Dosage & Administration
Dosage Guidelines
Recommended Dosage
• Amount: 30 mg
• Frequency: daily
• Duration: 4 weeks
• Rest Period: 12 weeks
• Time of Day: morning
• Ingestion: oral
Best taken 10-15 minutes before meals. Start with lower dose to assess tolerance.
Administration Routes:
- Oral
- Sublingual
Research Findings on Dosage:
Oral Capsules:
• Commonly Reported Dosage: 1-2 capsules (0.215 g each) twice daily (this equates to 20-40 mg of peptide complex A-20)
• Duration: 30-day cycles; repeat every 3–6 months as needed
Sublingual Solution:
• Commonly Reported Dosage: 5-6 drops under the tongue, 3-4 times per day
• Duration: 1 month, repeated every 3–6 months for maintenance
Administration Notes:
Best taken 10-15 minutes before meals
Anecdotally, users report improved energy, faster recovery after illness, and better resilience to stressors
Mechanism of Action
How this peptide works in the body
Activation of Hematopoietic Stem Cells
Bonomarlot's peptide complex interacts with nuclear DNA in bone marrow progenitor cells. This promotes transcription of genes involved in the self-renewal and differentiation of hematopoietic stem cells. As a result, the bone marrow increases output of erythrocytes (red blood cells), leukocytes (white blood cells), and thrombocytes (platelets), replenishing essential components of the immune and circulatory systems.
Restoration of Protein Synthesis in Bone Marrow
With aging or illness, protein synthesis in hematopoietic tissues declines. Bonomarlot reverses this decline by enhancing ribosomal activity and peptide signaling within stromal and stem cell niches. This facilitates cellular repair and optimizes the functional environment for blood cell maturation.
Immune Modulation Through Leukocyte Activation
By promoting the formation of functionally mature lymphocytes, neutrophils, and monocytes, Bonomarlot boosts innate and adaptive immunity. This includes improved antigen recognition, cytokine signaling, and phagocytic function, which are critical for infection control and tissue surveillance.
Systemic Regeneration and Anti-Aging Support
Enhanced hematopoiesis contributes indirectly to systemic regeneration by improving oxygen delivery, supporting mitochondrial biogenesis, and facilitating waste clearance via optimized circulation. This helps restore energy balance, supports wound healing, and contributes to age-related functional preservation.
Consider Stacking With
- Vladonix (thymus-based immune support)
- Ventfort (circulation and vascular health)
- Epitalon (anti-aging and telomere maintenance)
- Thymalin (immune balance and inflammatory modulation)
Side Effects & Cautions
Common Side Effects
- None reported in clinical or observational studies
Cautions
- Consult a healthcare provider if immunosuppressed or on blood-modifying medications
Research & References
Research Highlights
• Clinical studies on Bonomarlot's peptide complex show increased hematopoietic cell counts and faster recovery in patients with low immunity
• Long-term use associated with improved immune biomarkers and subjective vitality in older adults
• Shown to restore protein synthesis activity in aging bone marrow tissue
References
• Khavinson V. "Peptides and Ageing." Neuroendocrinology Letters, 2003
• Institute of Bioregulation and Gerontology. "Bone Marrow Peptides in Hematopoietic Restoration," Internal Monograph, 2011
• St. Petersburg Clinical Research Reports. "Cytomax A-20 Peptide Complex Applications in Hematology," 2015