Bibliography

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Curated references for Gas, Heat & Light Therapies.

Hydrogen Therapy

  1. Ohsawa I, et al. Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals. Nature Medicine. 2007;13(6):688-694.
  2. Yoritaka A, et al. Randomized, double-blind, multicenter trial of hydrogen water for Parkinson's disease. Movement Disorders. 2018;33(9):1505-1507.
  3. Tamura T, et al. Efficacy of inhaled hydrogen on neurological outcome following brain ischemia during post-cardiac arrest care. EClinicalMedicine. 2023;58:101907.
  4. LeBaron TW, et al. The effects of 24-week, high-concentration hydrogen-rich water on body composition, blood lipid profiles and inflammation biomarkers in men and women with metabolic syndrome. Diabetes, Metabolic Syndrome and Obesity. 2020;13:889-896.
  5. Sim M, et al. Hydrogen-rich water reduces inflammatory responses and prevents apoptosis of peripheral blood cells in healthy adults: a randomized, double-blind, controlled trial. Scientific Reports. 2020;10:12130.
  6. Zanini D, et al. The effects of 6-month hydrogen-rich water intake on molecular and phenotypic biomarkers of aging in older adults aged 70 years and over: A randomized controlled pilot trial. Experimental Gerontology. 2021;155:111574.
  7. Welsh C, et al. A widespread hydrogenase supports fermentative growth of gut bacteria in healthy people. Nature Microbiology. 2025;10:2686-2701.
  8. Cole AR, et al. Safety of prolonged inhalation of hydrogen gas in air in healthy adults. Critical Care Explorations. 2021;3(10):e543.

Red Light Therapy

  1. Laukkanen T, Khan H, Zaccardi F, Laukkanen JA. Association between sauna bathing and fatal cardiovascular and all-cause mortality events. JAMA Intern Med. 2015 Apr;175(4):542-8. doi: 10.1001/jamainternmed.2014.8187.
  2. Patrick RP, Johnson TL. Sauna use as a lifestyle practice to extend healthspan. Exp Gerontol. 2021 Oct 15;154:111509. doi: 10.1016/j.exger.2021.111509.
  3. Genuis SJ, Beesoon S, Lobo RA, Birkholz D. Human elimination of phthalate compounds: blood, urine, and sweat (BUS) study. ScientificWorldJournal. 2012;2012:615068. doi: 10.1100/2012/615068.
  4. Hamblin MR. Photobiomodulation or low-level laser therapy. J Biophotonics. 2016 Dec;9(11-12):1122-1124. doi: 10.1002/jbio.201670113.
  5. Lim L. Traumatic Brain Injury Recovery with Photobiomodulation: Cellular Mechanisms, Clinical Evidence, and Future Potential. Cells. 2024 Feb 23;13(5):385. doi: 10.3390/cells13050385.
  6. Swain M, K Soman S, Tapia K, Dagda RY, Dagda RK. Brain-derived neurotrophic factor protects neurons by stimulating mitochondrial function through protein kinase A. J Neurochem. 2023 Oct;167(1):104-125. doi: 10.1111/jnc.15945.
  7. Popp FA, Nagl W, Li KH, Scholz W, Weingärtner O, Wolf R. Biophoton emission. New evidence for coherence and DNA as source. Cell Biophys. 1984 Mar;6(1):33-52. doi: 10.1007/BF02788579.
  8. Kobayashi M, Takeda M, Sato T, Yamazaki Y, Kaneko K, Ito K, Kato H, Inaba H. In vivo imaging of spontaneous ultraweak photon emission from a rat's brain correlated with cerebral energy metabolism and oxidative stress. Neurosci Res. 1999 Jul;34(2):103-13. doi: 10.1016/s0168-0102(99)00040-1.
  9. Whelan HT, Buchmann EV, Dhokalia A, Kane MP, Whelan NT, Wong-Riley MT, Eells JT, Gould LJ, Hammamieh R, Das R, Jett M. Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice. J Clin Laser Med Surg. 2003 Apr;21(2):67-74. doi: 10.1089/104454703765035484.
  10. Chakravorty A, Jetto CT, Manjithaya R. Dysfunctional Mitochondria and Mitophagy as Drivers of Alzheimer's Disease Pathogenesis. Front Aging Neurosci. 2019 Nov 20;11:311. doi: 10.3389/fnagi.2019.00311.
  11. Kregel, K. C. (2002). Heat shock proteins: modifying factors in physiological stress responses and acquired thermotolerance. Journal of Applied Physiology, 92(5), 2177-2186. doi: 10.1152/japplphysiol.01267.2001.
  12. Calabrese, E. J., & Baldwin, L. A. (2003). Hormesis: the dose-response revolution. Annual Review of Pharmacology and Toxicology, 43, 175-197. doi: 10.1146/annurev.pharmtox.43.100901.140223.
  13. Laukkanen, J. A., Laukkanen, T., & Kunutsor, S. K. (2018). Cardiovascular and other health benefits of sauna bathing: a review of the evidence. Mayo Clinic Proceedings, 93(8), 1111-1121. doi: 10.1016/j.mayocp.2018.04.008.
  14. Chung H, Dai T, Sharma SK, Huang YY, Carroll JD, Hamblin MR. The nuts and bolts of low-level laser (light) therapy. Ann Biomed Eng. 2012 Feb;40(2):516-33. doi: 10.1007/s10439-011-0454-7.
  15. Tan DX, Reiter RJ, Zimmerman S, Hardeland R. Melatonin: Both a Messenger of Darkness and a Participant in the Cellular Actions of Non-Visible Solar Radiation of Near Infrared Light. Biology (Basel). 2023 Jan 6;12(1):89. doi: 10.3390/biology12010089.
  16. Genuis SJ, Birkholz D, Rodushkin I, Beesoon S. Blood, urine, and sweat (BUS) study: monitoring and elimination of bioaccumulated toxic elements. Arch Environ Contam Toxicol. 2011 Aug;61(2):344-57. doi: 10.1007/s00244-010-9611-5.
  17. Hamblin MR. Shining light on the head: Photobiomodulation for brain disorders. BBA Clin. 2016 Oct 1;6:113-124. doi: 10.1016/j.bbacli.2016.09.002.
  18. Itami N, Shirasuna K, Kuwayama T, Iwata H. Short-term heat stress induces mitochondrial degradation and biogenesis and enhances mitochondrial quality in porcine oocytes. J Therm Biol. 2018 May;74:256-263. doi: 10.1016/j.jtherbio.2018.04.010.
  19. Joneidi Z, Mortazavi Y, Memari F, Roointan A, Chahardouli B, Rostami S. The impact of genetic variation on metabolism of heavy metals: Genetic predisposition? Biomed Pharmacother. 2019 May;113:108642. doi: 10.1016/j.biopha.2019.108642.
  20. Wlodarczyk BJ, Zhu H, Finnell RH. Mthfr gene ablation enhances susceptibility to arsenic prenatal toxicity. Toxicol Appl Pharmacol. 2014 Feb 15;275(1):22-7. doi: 10.1016/j.taap.2013.12.014.